Mixing starts at that point really. Amazed at how many just don't take the time to get that right before hitting record. And yes, I once was one of those.
Mic placement is one of those "men from the boys" recording skills, one that doesn't get talked about that often.
Early in my audio career, I was fortunate to read a 1994 EQ magazine article by Steve Albini that really changed the way I looked at miking guitars. Even if you're not into his sound and aesthetic, there's a lot of thought provoking stuff in it.
And now, through the magic of the internet, you can read it too!